Evidence for memory improvement

Souvenaid is the first nutritional drink clinically proven to improve memory in early Alzheimer’s disease patients in two double-blind, randomised controlled trials [1,2]

Souvenaid efficacy was established in the Souvenir I and Souvenir II trials which demonstrated memory improvement in patients with mild AD, taking Souvenaid once-daily over 12 and 24 weeks, respectively [1,2].

Souvenir I

Souvenir I demonstrated that Souvenaid significantly improved memory performance (assessed by Wechsler Memory Scale-revised) and was well tolerated over a 12 week period in drug-naïve patients with mild Alzheimer’s disease.

Related Links:

Souvenir II

Souvenir II demonstrated that, over a 24-week period, Souvenaid provided significant improvements in memory performance (assessed by a Neuropsychological Test Battery) and was associated with a tolerability profile similar to controls in drug-free patients with mild Alzheimer’s disease.

Related links:


  1. Scheltens P, Kamphuis PJ, Verhey FR, Olde Rikkert MG, Wurtman RJ, Wilkinson D, Twisk JW, Kurz A.  Efficacy of a medical food in mild Alzheimer’s Disease: a randomized controlled trial. Alzheimer’s & Dementia. 2010;6:1-10.
  2. Scheltens P, Twisk JW, Blesa R, Scarpini E, von Arnim CA, Bongers A, Harrison J, Swinkels SH, Stam CJ, de Waal H, Wurtman RJ, Wieggers RL, Vellas B,Kamphuis PJ. Efficacy of Souvenaid in mild Alzheimer’s disease: results from a randomized, controlled trial. J Alzheimer’s Dis. 2012;31:225–236.